centre for kidney research

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Glomerulonephritis Research Group

This group studies the causes of and possible treatments for nephritis, the commonest cause of renal failure in children and adults in Australia.

It examines animal models of nephritis such as Heymann nephritis and also human forms of nephritis such as IgA nephropathy and acute crescentic GN. Our current focus of research is in T cell directed forms of immunothrerapy aimed at treating renal disease.

We currently have studies aimed at DNA vaccination against pathogenic TCR Vbetas and against chemokines thought to be pathogenic. These studies are done in collaboration with Dr David Harris at Westmead hospital.

Research Team

  • Steve Alexander
  • Yuan Min Wang